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This test is useful in determining whether or not ovulation has occurred. It also measures how the lining of the uterus responds to the hormones produced by the ovary. It is performed in the office, takes approximately five minutes to complete, and may be associated with mild discomfort. It is scheduled late in the menstrual cycle, usually two to three days before the onset of menses or ten to twelve days after an LH surge. For most women, this will be between the 24th and 27th day of their menstrual cycle.

Sometimes, there is spotting after a biopsy. If you have bleeding heavier than a menstrual period or a temperature above 100.4, call the office at which you are usually seen. It is important that you call with the onset of your next menstrual cycle so we can accurately interpret the biopsy results

It is very unlikely that an endometrial biopsy will harm a pregnancy conceived during the cycle it is performed. However, we recommend that you use a mechanical form of contraception, such as condoms, during that particular menstrual cycle. On occasion, when the biopsy is abnormal, it must be repeated during a subsequent cycle.

To schedule the endometrial biopsy, call the office at which you are usually seen, at the onset of your period the month you will have the test performed.